VASTO
Dual-MW Hyaluronic Acid ECM Hydration & Structural Foundation
- Dual-MW Hyaluronic Acid
- +35% ECM Hydration
- +42% Collagen Stimulation
VASTO is a next-generation skin booster engineered to restore extracellular matrix integrity, enhance deep hydration, and strengthen tissue architecture from within.
Dual-MW Hyaluronic Acid
+35% ECM Hydration
+42% Collagen Stimulation
Strengthens Structural Foundation
Clinical Problem
Loss of extracellular matrix stability, reduced hyaluronic acid content, and collagen degradation lead to dehydration, reduced elasticity, and compromised skin structure.
VASTO restores ECM hydration and promotes dermal remodelling for stronger, healthier skin.
Clinical Photography
Treatment Areas
Target Patient
Dehydrated,
dull skin
Loss of firmness
& elasticity
Ageing skin
with collagen loss
Post-procedure
recovery
Environmental stress
& pollution
Fine lines & early
ageing concerns
PRODUCT BENEFITS
Deep & long-lasting hydration
Improves elasticity & skin resilience
Stimulates collagen & ECM synthesis
Product Benefits
ECM Hydration
- Day 14
Dual-MW HA replenishes the dermal water reservoir — structural rehydration, not surface moisture.
Radiance Improvement
- Day 28
Enhanced light diffusion as ECM architecture is restored.
Elasticity Improvement
- Day 28
Skin ‘springs back’ — biomechanical elasticity restored.
Collagen Stimulation vs Control
VASTO primes fibroblasts for Phase 2.
Wound Recovery
- Day 7
Optimal healing environment post-procedure.
Product Composition
A scientifically engineered dual-molecular-weight hyaluronic acid system designed to restore extracellular matrix hydration, reinforce dermal architecture, and support long-tere skin quality improvement.
Ingredient
Function
5% HMW-HA (2,000 kDa)
Deep ECM architecture support — rebuilds the dermal scaffold
2.3% Low-MW Hyaluronic Acid
Surface hydration & epidermal barrier repair
0.7% High-MW HA
Structural volumising support · Total 150mg/5ml
Non-Crosslinked HA
Natural tissue integration — no inflammatory response
Pharmaceutical excipients
Physiological pH and osmolarity certified per lot
Clinical Performance
Mechanism of Action
Clinically validated healthcare platforms advancing regenerative aesthetics, microbiome science, and reproductive innovation.
Bioactive Delivery
ECM Rehydration
Fibroblast Priming
Angiogenic Support
Structural Remodelling
Clinical Performance
Clinical Performance.
Visibly Measured.
Neuvage™ VASTO delivers measurable improvements across key clinical endpoints related to skin hydration, regeneration, and structural foundation.
ECM Hydration
Day 0–14
Significantly improved extracellular matrix hydration and dermal moisture balance.
Collagen Synthesis
Day 28
Enhanced collagen I & III production and ECM remodelling.
Skin Elasticity
Day 28
Improved elasticity and skin resilience measured by cutometry.
Collagen Stimulation vs Control
Fibroblast activity increase and collagen stimulation within Days 7–14.
Wound Closure Improvement
Accelerated epithelialization and enhanced tissue repair process.
Recovery Speed
Day 7
Faster recovery and reduced inflammation compared to control.
Clinical Data over time
ECM Hydration Over Time
(% Increase vs Baseline)
ECM Hydration (day 14)
- Neuvage EGF
- Control
Collagen Synthesis Over Time
(% Increase vs Baseline)
Collagen Synthesis (Day 28)
- Neuvage EGF
- Control
Collagen Stimulation vs Control
(% Increase at Day 14)
Greater Collagen Stimulation
More Than Numbers. Real skin Benefits.
Deep Hydration
Restores ECM hydration and improves dermal moisture retention.
Stronger Skin Structure
Reinforces dermal architecture, improves structural support and barrier function.
Collagen Activation
Stimulates fibroblasts and collagen production for firmer, younger-looking skin.
Enhanced Recovery
Accelerates tissue repair and reduces downtime post-procedure.
Visible Rejuvenation
Improves elasticity, texture, and overall skin quality for radiant results.
Clinical Results
Induction Sessions
3 Sessions
Every 4 weeks
Volume per Session
2–3 mL
Per anatomical zone
Technique
Mesotherapy
32–300G micro-papules
Maintenance
Every 4–6 Months
Post completed induction
Treatment Areas
Face (Full) · Periorbital Zone · Neck · Hands · Décolletage · Post-Laser Recovery · Scar Management
Frequently Asked Questions
Scientific References
- Preclinical wound healing study · 155-subject · histological and angiogenic endpoints (p<0.01 vs matched control)
- Journal of Cosmetic Dermatology · ECM hydration and collagen stimulation data · validated methodology
- EU GMP manufacturing · Certificate of Analysis issued per lot · potency and sterility confirmed
Duration
All clinical data referenced from published peer-reviewed sources. For professional use by qualified healthcare providers only. Not for patient self-diagnosis or treatment.
