JUVI

50+ Bioactive Molecules Total Bio-Revitalisation Complex

JUVI is a next-generation bio-revitalisation solution powered by 50+ bioactive molecules to restore cellular energy, enhance skin metabolism, and promote visible, long-lasting rejuvenation.

Cellular Energy Restoration

Stimulates Collagen & Elastin

Improves Skin Structure

Enhances Radiance & Vitality

Strengthens Skin Resilience

Clinical Problem

Skin aging is a multi-factorial process — no single ingredient can address ECM fragmentation, mitochondrial failure, oxidative stress, and vascular decline simultaneously. Age 35+ patients require a comprehensive metabolic rejuvenation approach.

Clinical Photography

Treatment Areas

Target Patient

Patients 35–65+

with visible skin aging

Dull, fatigued skin

with uneven tone

High inflammatory burden

or oxidative stressed skin

Loss of firmness

& facial contour sagging

Post-JUVI + EGF

Phase 3 protocol patients

Patients seeking

bio-revitalisation and radiance enhancement

PRODUCT BENEFITS

Restores Cellular Energy

& Mitochondrial Function

Boosts Collagen

& Elastin Production

Reduces Oxidative

Stress & Inflammation

Improves Skin Quality,

Tone & Radiance

Product Benefits

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ECM Hydration

Significantly improves extracellular matrix hydration and moisture balance.

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Collagen Synthesis

Enhanced collagen I & III production and ECM remodeling.

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Skin Elasticity

Improved elasticity and skin resilience measured by cutometry.

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Collagen Stimulation vs Control

Fibroblast activity increase and collagen stimulation within Days 7–14.

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Wound Closure Improvement

Accelerated epithelialization and enhanced tissue repair process.

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Recovery Speed

Faster recovery and reduced inflammation compared to control.

Product Composition

JUVI combines 50+ bioactive molecules including multi-molecular-weight hyaluronic acid, peptides, amino acids, vitamins, cofactors, and antioxidants to deliver comprehensive cellular rejuvenation and long-term skin vitality.

Ingredient

Function

Hyaluronic Acid (Multi-MW)

Non-crosslinked HA • Depth-targeted hydration • Micro-MW texture support • Long-lasting moisture retention

Amino Acids (15+)

 Collagen precursors: Proline, Lysine, Cysteine, Leucine • ECM building blocks • Supports skin repair and firmness

Vitamins & Cofactors

Vit C, B1-B12, E • Antioxidant protection • Glutathione, CoQ10 • Magnesium, Zinc, Selenium • Cellular energy boost • Supports enzymatic function

Peptides & Growth Factors

 GHK-Cu • Palmitoyl pentapeptide • Fibronectin activators • Nucleotides • Stimulates cell communication • Promotes collagen synthesis and tissue regeneration

Antioxidants (5)

Multi-pathway ROS scavenging • -60% oxidative stress reduction • Protects DNA and proteins • Delays cellular aging

Clinical Performance

Mechanism of Action

Neuvage™ JUVI works through a Total Bio-Revitalization Mechanism that reactivates cellular energy, protects against oxidative stress, stimulates matrix regeneration, and improves microcirculation for comprehensive skin rejuvenation.

MULTI-LAYER BIOACTIVE DELIVERY

Multi-MW hyaluronic acid, amino acids, vitamins, and nucleotides are delivered throughout the epidermis and dermis, providing comprehensive metabolic nourishment.

CELLULAR ENERGY REACTIVATION

CoQ10, coenzymes, and cellular cofactors reactivate mitochondrial ATP production, restoring fibroblast activity and cellular metabolism.

OXIDATIVE STRESS DEFENSE

Glutathione, Vitamin C, and antioxidant nutrients reduce oxidative stress, protecting cellular structures and preserving tissue integrity.

FIBROBLAST & MATRIX ACTIVATION

Amino acids, peptides, and growth factors stimulate fibroblast function, initiating collagen, elastin, and extracellular matrix synthesis.

MICROCIRCULATION & TISSUE VITALITY

Growth peptides and bioactive nutrients support angiogenic signaling and tissue oxygenation, improving nutrient delivery and skin vitality.

ECM REMODELING & SKIN RENEWAL

Continuous collagen organization, elastin reinforcement, and ECM remodeling improve firmness, elasticity, texture, and radiance.

Clinical Performance

Clinical Performance.
Total Bio-Revitalization. Visibly Proven.

Neuvage™ JUVI delivers measurable improvements in skin rejuvenation, collagen density, oxidative stress reduction, hydration, elasticity, and microcirculation through its 50+ bioactive molecule complex.

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Wound Closure

Day 0–14

Accelerated tissue regeneration and epidermal recovery.

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Collagen Deposition

Enhanced collagen matrix formation and dermal restructuring.

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ROS Reduction

Significant reduction in oxidative stress burden.

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Skin Elasticity

Improved firmness and mechanical resilience.

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ECM Hydration

Day 0–14

Restored extracellular matrix hydration and moisture balance.

0 CCM

Microvascular Density (Vessels/Field)

Enhanced angiogenesis and tissue nourishment.

Clinical Data over time

Wound Closure Over Time

(Percentage of Wound Area Closed)

ECM Hydration (day 14)
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Collagen Deposition Over Time

(% Increase in collagen Density)

Skin Elasticity (Day 28)
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Wound Closure Over Time

(Percentage of Wound Area Closed)

Collagen Deposition
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More Than Numbers. Real skin Benefits.

Radiant Glow
Brighter, healthier-looking skin with improved radiance and vitality.
Smoother Skin Texture

Refines rough skin texture for a softer and more polished look

Improved Firmness

Skin feels firmer with improved elasticity and facial contour.

More Even Skin Tone

Reduces dullness and uneven appearance for a balanced tone.

Youthful Rejuvenation

Overall skin quality enhancement with a fresher, revitalized look.

Clinical Results

Induction Sessions

3 Sessions

Every 2.5–4 weeks

Volume per Session

2–4 mL

Per anatomical area

Protocol Position

Phase 3

Following VASTO + EGF induction

Maintenance

1–2 Sessions

Every 3–6 months

Treatment Areas

Face (Full) · Periorbital · Hands & Elbows · Neck & Décolletage · Body · Bikini & Intimate Area

Frequently Asked Questions

Why does JUVI contain 50+ bioactive molecules?
Skin aging is multi-factorial. No single molecule can address ECM fragmentation, mitochondrial failure, oxidative stress, and vascular decline simultaneously. JUVI's 50+ bioactives each target a specific pathway — in synergy, they execute a complete rejuvenation cascade.
 
Can JUVI be used independently of VASTO and EGF?
Yes — JUVI is effective as a standalone bio-revitalisation product. Its efficacy is maximised as Phase 3 of the Neuvage Protocol, where VASTO primes ECM hydration and EGF regenerates the cellular environment first.

Scientific References

  1. Preclinical wound healing study · 155-subject · Masson-Goldner staining · collagen quantification endpoints · p<0.001
  2. CCM (Confocal Corneal Microscopy) microcirculation assessment · 25.0 vessels/field validated
  3. EU GMP manufacturing · 50+ bioactive formulation stability confirmed · Certificate of Analysis per lot
Duration

All clinical data referenced from published peer-reviewed sources. For professional use by qualified healthcare providers only. Not for patient self-diagnosis or treatment.

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