VASTO Question Bank

Section 1: Hyaluronic Acid Basics

What type of molecule is Hyaluronic Acid?

a) Protein
b) Carbohydrate
c) Glycosaminoglycan
d) Lipid

Section 1: Hyaluronic Acid Basics

What are the two sugars that make up Hyaluronic Acid?

a) Glucose and Fructose
b) Galactose and Mannose
c) Glucuronic Acid and N-acetylglucosamine
d) Sucrose and Lactose

Section 1: Hyaluronic Acid Basics

Where is Hyaluronic Acid naturally found in the human body?

a) Bloodstream
b) Skin, joints, and eyes
c) Hair and nails
d) Liver and kidneys

Section 1: Hyaluronic Acid Basics

Which enzyme is responsible for the production of Hyaluronic Acid?

a) Amylase
b) Hyaluronidase
c) Hyaluronan synthases
d) Lactase

Section 1: Hyaluronic Acid Basics

What percentage of Hyaluronic Acid is found in the skin?

a) 10%
b) 27%
c) 56%
d) 75%

Section 2: Hyaluronic Acid Properties and Distribution

What is the water-binding capacity of Hyaluronic Acid?

a) Up to 100 times its volume
b) Up to 200 times its volume
c) Up to 500 times its volume
d) Up to 1000 times its volume

Section 2: Hyaluronic Acid Properties and Distribution

Which form of Hyaluronic Acid penetrates deeper into the skin?

a) Sodium Hyaluronate
b) High Molecular Weight HA
c) Low Molecular Weight HA
d) Medium Molecular Weight HA

Section 2: Hyaluronic Acid Properties and Distribution

Which tissues contain the highest concentration of Hyaluronic Acid?

a) Muscles
b) Skeleton and support tissue
c) Skin
d) Intestine and stomach

Section 2: Hyaluronic Acid Properties and Distribution

What is the primary advantage of bacterial-based synthesis of Hyaluronic Acid?

a) Lower cost
b) No allergenic risks
c) Faster production
d) Higher molecular weight

Section 2: Hyaluronic Acid Properties and Distribution

What molecular weight of Hyaluronic Acid is used for wound healing?

a) >1000 kDa
b) 10 kDa – 1000 kDa
c) 100 – 250 kDa
d) ≤10 kDa

Section 3: Hyaluronic Acid Mechanism and Functions

Which enzyme is involved in the degradation of Hyaluronic Acid?

a) Hyaluronidase
b) Collagenase
c) Elastase
d) Protease

Section 3: Hyaluronic Acid Mechanism and Functions

How is Hyaluronic Acid primarily excreted from the body?

a) Through the liver
b) Through the kidneys
c) Through the lungs
d) Through the intestines

Section 3: Hyaluronic Acid Mechanism and Functions

What is the primary function of Hyaluronic Acid in the skin?

a) Collagen production
b) Water retention and hydration
c) Skin pigmentation
d) Fat storage

Section 3: Hyaluronic Acid Mechanism and Functions

Which molecular weight of Hyaluronic Acid is associated with surface hydration?

a) Low Molecular Weight HA
b) Medium Molecular Weight HA
c) High Molecular Weight HA
d) Ultra Low Molecular Weight HA

Section 3: Hyaluronic Acid Mechanism and Functions

What effect does Low Molecular Weight Hyaluronic Acid have on the skin?

a) Increases skin elasticity
b) Enhances skin hydration
c) Promotes fibroblast proliferation
d) Reduces skin pigmentation

Section 4: Hyaluronic Acid Applications and Preparation

Which of the following is a natural source of Hyaluronic Acid?

a) Bacterial fermentation
b) Synthetic production
c) Rooster combs
d) Human plasma

Section 4: Hyaluronic Acid Applications and Preparation

What is the risk associated with animal-based Hyaluronic Acid?

a) High production cost
b) Allergic and infectious risks
c) Low molecular weight
d) Poor absorption

Section 4: Hyaluronic Acid Applications and Preparation

Which of the following is NOT a property of Cross-Linked Hyaluronic Acid?

a) Gel-like consistency
b) Longer-lasting effects
c) Rapid degradation
d) Injectable forms for dermal fillers

Section 4: Hyaluronic Acid Applications and Preparation

Which substance is used in the cross-linking of Hyaluronic Acid?

a) BDDE (1,4-Butanediol Diglycidyl Ether)
b) Sodium chloride
c) Ethanol
d) Glycerin

Section 4: Hyaluronic Acid Applications and Preparation

In what form does natural Hyaluronic Acid exist?

a) Gel
b) Powder
c) Viscous liquid
d) Solid

Section 5: Hyaluronic Acid in Clinical Use

Which of the following is a common side effect of Hyaluronic Acid injections?

a) Permanent scarring
b) Temporary swelling
c) Severe allergic reactions
d) Skin discoloration

Section 5: Hyaluronic Acid in Clinical Use

Which skin condition is Hyaluronic Acid most commonly used to treat?

a) Eczema
b) Psoriasis
c) Acne
d) Wrinkles and fine lines

Section 5: Hyaluronic Acid in Clinical Use

How long do the effects of skin boosters typically last?

a) 1-2 weeks
b) 1-2 months
c) 3-6 months
d) 1 year

Section 5: Hyaluronic Acid in Clinical Use

What is the typical half-life of Hyaluronic Acid in the bloodstream?

a) 3-5 minutes
b) 1-2 hours
c) 1 day
d) 1 week

Section 5: Hyaluronic Acid in Clinical Use

Which of the following is a benefit of Cross-Linked Hyaluronic Acid over Non-Cross-Linked?

a) Faster absorption
b) Longer duration
c) Higher viscosity
d) Lower cost